The copper binding properties of metformin--QCM-D, XPS and nanobead agglomeration.
نویسندگان
چکیده
Study of the copper binding properties of metformin is important for revealing its mechanism of action as a first-line type-2 diabetes drug. A quantitative investigation of interactions between metformin and L-cysteine-copper complexes was performed. The results suggest that metformin could interact with biological copper, which plays a key role in mitochondrial function.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 97 شماره
صفحات -
تاریخ انتشار 2015